mice with an extract of lion's mane mycelium and fruiting body and confirmed that it promoted neurogenesis in the hippocampus and objects this puffy white mushroom that resembles a lion's mane has been used as both food and medicine in east asian countries for one of lion mane's most unique properties is its ability to increase that allows nerve signals to be sent and received quickly and has been found to promote nerve regeneration and functional recovery after severe nerve injury because of its multiple actions in the central nervous system researchers are investigating lion's mane's therapeutic potential controlled study of 50-to 80-year-old japanese women and men with mild cognitive impairment found that lion's mane improved higher scores on a cognitive function scale compared with the taken long term oxidative damage and neurotoxicity and preventing cell shrinkage another animal model of alzheimer's found that an alcohol extract of the mycelium reduced amyloid beta plaque in & restful sleep been used as a medicinal mushroom for more than 2,000 years western science has largely focused on reishi's role in immunity with a number of studies finding that reishi-including the fruiting body and the mycelium-contains polysaccharides that enhance immune function and activate the immune response research has shown that the polysaccharides in reishi are potent immunomodulators that exert “a significant and comprehensive impact on immune cells...” including enhancing the proliferation have also been shown to exhibit antiviral and antibacterial actions and animal research has demonstrated that the fruiting body of reishi does significantly increase total sleep time and non-rapid was published showing that reishi has a positive effect on the found that an extract of reishi was an effective treatment for "neurasthenia," a medical condition characterized by physical and of supplementing with a reishi extract at 1,800 mg three times fatigue and in overall sense of wellbeing